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By Amy Norton , Reuters Health. The honey, produced from the nectar of a particular rhododendron species, has long been linked to food poisoning, with most of the documented cases seen in Turkey. Reporting in the Annals of Emergency Medicine, Turkish researchers document 21 cases of mad-honey poisoning that passed through their ER over five years.

Nearly all patients were middle-aged and older men -- a demographic that, according to local beekeepers, usually buys mad honey as a way to enhance sexual performance. The problem with mad honey is its concentration of substances called grayanotoxins, some of which can cause low blood pressure, slowed heart rate, vomiting, dizziness and fainting.

Poisoning typically happens because the consumer downs more mad honey than is recommended, Demircan told Reuters Health in an . For their study, Demircan and his colleagues reviewed the records of more than , patients treated in their ER between December and January They identified 21 cases of mad-honey poisoning; patients typically developed symptoms like dizziness, nausea and vomiting about one hour after ingesting the honey.

Of the 21 patients, 18 were men, and the group as a whole ranged in age from 41 to All were treated successfully and released from the hospital within 18 to 48 hours, the researchers report. According to beekeepers, men in their 40s and 50s usually seek out the honey to improve their sexual function. The findings, according to Demircan, suggest that ER doctors should consider the possibility of mad-honey poisoning in cases where low blood pressure and slowed heart rate cannot be attributed to other, more common causes -- especially in middle-aged men. And while most cases have been seen in Turkey, the researcher said that ERs elsewhere should be aware of mad-honey poisoning.

He pointed to case reports from Europe where men of Turkish descent ended up in the ER with apparent mad-honey poisoning. Processed honey is unlikely to contain grayanotoxins.

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